Enantioselective Reductions of Prochiral Ketones by Means of Oxazaborolidines

Authors

  • M. Taraba* *Spolana, ZKCH, Neratovice, **Department of Organic Chemistry, Institute of Chemical Technology, Prague
  • J. Palecek** *Spolana, ZKCH, Neratovice, **Department of Organic Chemistry, Institute of Chemical Technology, Prague

Abstract

The possibilities of synthetic utilization of enantioselective reductions of prochiral ketones catalyzed by 1,2,3-oxazaborolidines are shown on a series of representative pattern reactions. The presented reactions are evaluated from the point of view of reaction conditions, i.e. type and amount of the used catalyst, reduction agent (BH3.THF, BH3.SMe3, catecholborane), solvent (THF, toluene, CH2Cl2, i.a.) or activator (simple alcohols or ethanolamine).

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Published

1997-02-15

How to Cite

Taraba*, M., & Palecek**, J. (1997). Enantioselective Reductions of Prochiral Ketones by Means of Oxazaborolidines. Chemické Listy, 91(1). Retrieved from http://w-ww.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/2802

Issue

Vol. 91 No. 1 (1997)

Section

Articles